EBUS TBNA Adequacy Assessment
Rapid on-site evaluation (ROSE) Solution for EBUS-TBNA that assists in adequacy assessment, diagnosis, and staging of lung cancer.
- Rapid on-site evaluation (ROSE) for adequacy assessment of EBUS-TBNA aspirates.
- Aids accurate and faster diagnosis and staging of lung cancer.
- Analyses of whole slide images of conventional PAP (Papanicolaou) stained cytology smears.
- Rapid onsite reporting with increased yield eliminating need for repeat procedures.
- Optimised hospital stay and cost benefits to the patient.
- Objective, evidence-based, and precise reports with fewer reviews.
- 24/7 reporting with batch analysis.
- Strong agreement of 0.92 (Cohen’s Kappa) with manual adequacy assessment by pathologists.




Tumor Identification and Localization
- Algorithms for identification and segmentation of tumours in Hematoxylin and Eosin (H&E) stained whole slide images.
- Algorithm features include: tumour identification, tumour/stroma segmentation and tumour localization.
- Algorithm outputs validated for use on Non Small Cell Lung Carcinoma (NSCLC), breast carcinoma, pancreatic ductal adenocarcinoma and Head and Neck Squamous Cell Carcinoma (HNSCC).
ER/PR Quantification in Breast Carcinoma
- Solution for accurate quantification of Estrogen/Progesterone receptor expression in breast carcinoma.
- Aids disease stratification, prognostication and treatment decisions.
- Segmentation and quantification models of tumour nuclei (positive and negative) to compute Allred scores.
- Automated exclusion of in-situ malignancy from quantification.
- Available as both semi-automated and automated workflow solutions.
- Applicable on selected regions of interest (ROI) as well as whole slide images.
- Improves accuracy, reproducibility and throughput of biomarker reporting.
- Very good agreement with pathologists; Sensitivity, Precision, and F1-score of 0.99, 0.84, 0.91 respectively .




Her-2/Neu Quantification in IDC Breast
- Solution for accurate quantification of Her-2/Neu expression in breast carcinoma.
- Aids disease stratification, prognostication and treatment decisions.
- Segmentation, quantification and grading of membrane positivity and intensity.
- Automated exclusion of in-situ malignancy from quantification.
- Available as both semi-automated and automated workflow solutions.
- Applicable on selected regions of interest (ROI) as well as whole slide images .
- Improves accuracy, reproducibility and throughput of biomarker reporting.
- Strong agreement (0.91 Quadratic Kappa) with pathologists scoring.
Mitotic Index Quantification
- Solution for mitotic index calculation.
- Aids in prognostication, disease stratification and treatment decisions.
- Applicable to Hematoxylin and Eosin based sections from breast carcinoma and Head & Neck Squamous Cell Carcinoma (HNSCC).
- Analyses of “field of view” images as well as whole slide images.
- Provides mitotic figure segmentation, classification, with improved accuracy of mitotic index calculation.
- Strong and significant correlation (r = 0.91, p <.001) with manual assessment methods.




Gleason grading
- Solution to aid accurate disease stratification in prostate carcinoma.
- Automated tumour/stroma segmentation.
- Pixel level Gleason grading as well as section level Gleason scoring.
- Applicable on Tissue Micro Arrays (TMA), needle core biopsies, and radical resection specimens.
Pancreatic Intraepithelial Neoplasia (PanIN)
- PanIN are microscopic epithelial precursor lesions of pancreatic ductal adenocarcinoma (PDAC) that serve as surrogate markers for invasive carcinoma elsewhere in the organ.
- Solution for segmentation of PanIN lesions in Hematoxylin and Eosin (H&E) stained sections of human pancreas.
- Accurate segmentation, grading of PanIN regions and invasive carcinoma in whole slide images of pancreas.
- Sensitivity of 91.56% and Specificity of 85.68% in comparison with manual assessment by pathologists, for detection of PanIN.




Radical Prostatectomy Reporting
- Solution for comprehensive reporting of Radical Prostatectomy specimens.
- Gleason grading and staging with quantification of primary, secondary and tertiary patterns.
- Segmentation and quantification of additional diagnostic, prognostic and predictive parameters to aid disease stratification, prognostication and treatment decisions.
- Synoptic, customizable reporting formats.
- Correlation with multi-modality data, to improve accuracy of reporting.
PDL-1 Quantification in NSCLC
- PD-L1 protein expression has emerged as a biomarker with capabilities to predict patient response to immunotherapy.
- Algorithm to aid patient selection for treatment with anti PD1/PDL-1 antibodies in lung carcinoma.
- Networks for tumour segmentation, tumour cell detection and classification, with computation of the Tumour Proportion Score (TPS).
- Both semi-automated and automated workflows available.
- Applicable to selected regions of interest (ROI) as well as whole slide images.




Retinal Disease Classification and Grading
- Solutions for retinal disease identification, diagnosis and grading.
- Classification and grading of retinal diseases like Diabetic Retinopathy, Age-related Macular Degeneration, Glaucoma, and others, using colour fundus images.
- Sensitivity for retinal disease classification across classes range between 88% to 99%.
NOTE: Unless otherwise stated, all products are “Research Use Only”; not for use in diagnostic procedures.